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California Heart & Lung Surgery Medical Center
Alexander Marmureanu, MD

Alexander Marmureanu

Alexander Marmureanu

Lung cancer is the most common form of cancer in the United States. With 170,000 new cases each year, it is the leading cause of death from cancer. Early detection can improve survival. When lung cancer is further advanced, surgery in combination with chemotherapy or radiation therapy may still be curative.

The term chronic obstructive pulmonary disease (COPD) or Chronic Obstructive Lung Disease (COLD) labels the group of diseases linked by a common difficulty in expelling air from the lungs. The three diseases most commonly termed COPD or COLD are asthma, chronic bronchitis, and emphysema.

Interstitial lung disease & pulmonary fibrosis
are general terms used to describe inflammatory and fibrotic disorders of interstitium (lung tissue). There are over 100 known causes of interstitial lung disease and pulmonary fibrosis, including familial and genetic disorders, inhaled substances, infections, medications, and connective tissue diseases.

Hyperhidrosis refers to excessive sweating in the hands, feet, and other regions of the body that is caused by hyperactivity of the autonomic nervous system. Approximately 1% of adults are estimated to suffer from hyperhidrosis, which can be treated medically or through a non-invasive surgical procedure known as an endoscopic thoracic sympathectomy (ETS).

We have wide experience in the management of benign and malignant esophageal disease, including Barrett’s Disease. The prevalence of the most common form of esophageal cancer, adenocarcinoma, is increasing faster than any other tumor in North America.

Gastroesophageal reflux disease (GERD), a common digestive disorder with symptoms of heartburn, is a much less dangerous form of esophageal disease that afflicts millions of Americans each year.

Mesothelioma is a lung disease that occurs mainly in men over the age of 50 and is frequently associated with prior environmental or occupational exposure to asbestos. It can be diagnosed only by biopsy. Treatment often requires major surgery on the pleura (the lining membrane of the lung) and the lung and may involve post-surgical chemotherapy and radiation treatment.

Myasthenia gravis is an autoimmune disorder causing muscular weakness. Our current research efforts are directed towards the development of a more standardized staging system to allow comparison of different medical and surgical therapies, including robotically assisted minimally invasive thymectomy (removal of the thymus gland). Our team approach—including specialists in neurology, pain management, pulmonology, and critical care—has dramatically improved the effectiveness and safety of thymectomy, which can now be recommended even for patients with advanced muscle weakness.

Pectus excavatum is an abnormal development of the chest wall in which several ribs and the sternum grow abnormally, resulting in a caved-in, or sunken appearance. Our goal is to provide complete clinical resources for the patient and family for diagnosis and decisionmaking about treatment, and if surgical treatment is chosen, for recovery, rehabilitation, and return to school or work, and exercise. We are able to treat most patients, both adolescents and adults with pectus excavatum using minimally invasive techniques.

Pulmonary (lung) artery blockages are divided into two categories due to their different treatment requirements. Acute pulmonary embolism, treated with medication and occasionally with surgery, is a sudden, life-threatening, blockage in the arteries of the lung that occurs when a clot in a vein elsewhere in the body travels to the lung. Ongoing blockage of the pulmonary arteries occurs when clots and other matter from the blood builds up in the vessel, inhibiting or blocking the path of blood flow, and causes a condition known as chronic thromboembolic pulmonary hypertension (CTEPH).

Cystic fibrosis is a severe, genetically-determined disease involving the lungs and gastrointestinal tract, as well as other organs. This disease affects the glands that secrete sweat and mucus. Cystic fibrosis is often treated at home with antibiotics and special exercises for draining mucus in the chest.

Thoracic Outlet Syndrome (TOS) is a term used to describe symptoms which arise from the compression of the subclavian (under the collarbone) artery or vein. The diagnosis is often controversial because there is no universally accepted test to confirm the presence of the compression.

Lung Diseases & Disorders